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Structural basis for virulence activation of Francisella tularensis
The bacterium, Francisella tularensis (Ft), is one of the most infectious agents known. Ft virulence is controlled by a unique combination of transcription regulators: the MglA-SspA heterodimer, PigR, and the stress signal, ppGpp. MglA-SspA assembles with the σ(70)-associated RNAP holoenzyme (RNAPσ(...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7959165/ https://ncbi.nlm.nih.gov/pubmed/33217319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.035 |
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