The role of extracellular vesicles and PD-L1 in glioblastoma-mediated immunosuppressive monocyte induction

BACKGROUND: Immunosuppression in glioblastoma (GBM) is an obstacle to effective immunotherapy. GBM-derived immunosuppressive monocytes are central to this. Programmed cell death ligand 1 (PD-L1) is an immune checkpoint molecule, expressed by GBM cells and GBM extracellular vesicles (EVs). We sought...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Himes, Benjamin T, Peterson, Timothy E, de Mooij, Tristan, Garcia, Luz M Cumba, Jung, Mi-Yeon, Uhm, Sarah, Yan, David, Tyson, Jasmine, Jin-Lee, Helen J, Parney, Daniel, Abukhadra, Yasmina, Gustafson, Michael P, Dietz, Allan B, Johnson, Aaron J, Dong, Haidong, Maus, Rachel L, Markovic, Svetomir, Lucien, Fabrice, Parney, Ian F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339906/
https://ncbi.nlm.nih.gov/pubmed/32080744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa029
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge