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IT-18 GLIOBLASTOMA STAT3 AND PD-L1 EXPRESSION DRIVES ACCUMULATION OF IMMUNOSUPPRESSIVE LEUKOCYTES
BACKGROUND: Glioblastoma (GBM) is a devastating disease with a median survival of 14 months. Immunotherapies hold promise but are compromised by tumor-mediated immunosuppression including accumulation of regulatory T-cells (T(REG)'s) and myeloid-derived suppressor cells (MDSC's). Mechanism...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218234/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.16 |
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