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Assessment of circulating tumor DNA in cerebrospinal fluid by whole exome sequencing to detect genomic alterations of glioblastoma

BACKGROUND: Cerebrospinal fluid (CSF) has been demonstrated as a better source of circulating tumor DNA (ctDNA) than plasma for brain tumors. However, it is unclear whether whole exome sequencing (WES) is qualified for detection of ctDNA in CSF. The aim of this study was to determine if assessment o...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Chin Med J (Engl)
Main Authors: Duan, Hao, Hu, Ji-Long, Chen, Zheng-He, Li, Jue-Hui, He, Zhen-Qiang, Wang, Zhen-Ning, Zhang, Guan-Hua, Guo, Xiao-Yu, Liang, Lun, Mou, Yong-Gao
פורמט: Artigo
שפה:Inglês
יצא לאור: Wolters Kluwer Health 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339330/
https://ncbi.nlm.nih.gov/pubmed/32558704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000843
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