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Assessment of circulating tumor DNA in cerebrospinal fluid by whole exome sequencing to detect genomic alterations of glioblastoma

BACKGROUND: Cerebrospinal fluid (CSF) has been demonstrated as a better source of circulating tumor DNA (ctDNA) than plasma for brain tumors. However, it is unclear whether whole exome sequencing (WES) is qualified for detection of ctDNA in CSF. The aim of this study was to determine if assessment o...

詳細記述

保存先:
書誌詳細
出版年:Chin Med J (Engl)
主要な著者: Duan, Hao, Hu, Ji-Long, Chen, Zheng-He, Li, Jue-Hui, He, Zhen-Qiang, Wang, Zhen-Ning, Zhang, Guan-Hua, Guo, Xiao-Yu, Liang, Lun, Mou, Yong-Gao
フォーマット: Artigo
言語:Inglês
出版事項: Wolters Kluwer Health 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339330/
https://ncbi.nlm.nih.gov/pubmed/32558704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000843
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