MBRS-26. WHOLE EXOME SEQUENCING OF CIRCULATING TUMOR DNA EXTRACTED FROM THE CEREBROSPINAL FLUID ALLOWS A PANGENOMIC CHARACTERISTISATION OF THE PRIMARY TUMOR

BACKGROUND: Liquid biopsies are revolutionary tools to detect tumour-specific genetic alterations in body fluids. Here, we assess whether the circulating tumor DNA (ctDNA) in Cerebral Spinal Fluid (CSF) could be used for tumor genetic profiling of Medulloblastomas (MB). METHODS: We extracted the ctD...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Chicard, Mathieu, Combaret, Valérie, Danzon, Adrien, Clément, Nathalie, Masliah-Planchon, Julien, Bohec, Mylène, Baulande, Sylvain, Pouponnot, Célio, Frappaz, Didier, Doz, François, Delattre, Olivier, Schleiermacher, Gudrun, Bourdeaut, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012875/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.471
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