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IGFBP3 inhibits angiogenesis through intracellular regulation of THBS1 expression

Insulin-like growth factor binding protein-3 (IGFBP3) has been postulated to be a mediator of growth suppression signaling. It was shown to function as a suppressor of invasion in epithelial ovarian cancer (EOC). In this study, we identified an angiogenesis inhibitor, thrombospondin-1 (THBS1), which...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Shih, Ho-Jun, Chen, Chi-Ling, Torng, Pao-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339270/
https://ncbi.nlm.nih.gov/pubmed/32642286
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