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Promoter methylation of IGFBP-3 and p53 expression in ovarian endometrioid carcinoma

BACKGROUND: Insulin-like growth factor binding protein (IGFBP-3) is an antiproliferative, pro-apoptotic and invasion suppressor protein which is transcriptionally regulated by p53. Promoter methylation has been linked to gene silencing and cancer progression. We studied the correlation between IGFBP...

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Hlavní autoři: Torng, Pao-Ling, Lin, Ching-Wei, Chan, Michael WY, Yang, Hui-Wen, Huang, Su-Cheng, Lin, Chin-Tarng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799391/
https://ncbi.nlm.nih.gov/pubmed/20003326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-120
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