CFTR promotes malignant glioma development via up‐regulation of Akt/Bcl2‐mediated anti‐apoptosis pathway

Cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP‐activated Cl(‐) channel, is extensively expressed in the epithelial cells of various tissues and organs. Accumulating evidence indicates that aberrant expression or mutation of CFTR is related to carcinoma development. Malignant glio...

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Publicat a:J Cell Mol Med
Autors principals: Zhao, Mingyue, Zhang, Jieting, Huang, Wenqing, Dong, Jianda, Guo, Jinghui, U, Kin Pong, Weng, ZhiHui, Liu, Si, Chan, Hsiao Chang, Feng, Hua, Jiang, Xiaohua
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339181/
https://ncbi.nlm.nih.gov/pubmed/32463592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15300
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