CFTR promotes malignant glioma development via up‐regulation of Akt/Bcl2‐mediated anti‐apoptosis pathway

Cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP‐activated Cl(‐) channel, is extensively expressed in the epithelial cells of various tissues and organs. Accumulating evidence indicates that aberrant expression or mutation of CFTR is related to carcinoma development. Malignant glio...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhao, Mingyue, Zhang, Jieting, Huang, Wenqing, Dong, Jianda, Guo, Jinghui, U, Kin Pong, Weng, ZhiHui, Liu, Si, Chan, Hsiao Chang, Feng, Hua, Jiang, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339181/
https://ncbi.nlm.nih.gov/pubmed/32463592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15300
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