Bag‐1 and Bcl‐2 Gene Transfer in Malignant Glioma: Modulation of Cell Cycle Regulation and Apoptosis

Bag‐1 is a heat shock 70 kDa (Hsp70)‐binding protein that can collaborate with Bcl‐2 in suppressing apoptosis under some conditions. Here, we report that 11 of 12 human glioma cell lines express Bag‐1 protein in vitro. Moreover, 15 of 19 human glioblastomas expressed Bag‐1 as assessed by immunohisto...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Roth, Wilfried, Grimmel, Cornelia, Rieger, Lorenz, Strik, Herwig, Takayama, Shinichi, Krajewski, Stanislaw, Meyermann, Richard, Dichgans, Johannes, Reed, John C., Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Research Article‐
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098428/
https://ncbi.nlm.nih.gov/pubmed/10764042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2000.tb00256.x
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