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Anti-apoptotic genes, bag-1 and bcl-2, enabled hybridoma cells to survive under treatment for arresting cell cycle

Hybridoma 2E3-O cells were transfected with bcl-2 alone or with bcl-2 and bag-1 in combination. The bcl-2/bag-1 transfectant survived maintaining viability above 75% for almost 5 days when the cells were treated with excess (30 mM) thymidine for arresting cell cycle, whereas the mock transfectant su...

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Detalhes bibliográficos
Main Authors: Terada, Satoshi, Fukuoka, Katsuyuki, Fujita, Tetsuo, Komatsu, Tomoaki, Takayama, Shinichi, Reed, John C., Suzuki, Eiji
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466758/
https://ncbi.nlm.nih.gov/pubmed/9474804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1007954103572
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