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Establishing apoptosis resistant cell lines for improving protein productivity of cell culture

The authors established apoptosis resistant COS–1, myeloma, hybridoma, and Friend leukemia cell lines by genetically engineering cells, aiming at more efficient protein production by cell culture. COS–1 cells, which are most widely used for eukariotic gene expression, were transfected with human bcl...

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Detalhes bibliográficos
Main Authors: Suzuki, Eiji, Terada, Satoshi, Ueda, Hiroshi, Fujita, Tetsuo, Komatsu, Tomoaki, Takayama, Shinichi, Reed, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449862/
https://ncbi.nlm.nih.gov/pubmed/22358521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1007942929800
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