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Insulin receptor endocytosis in the pathophysiology of insulin resistance

Insulin signaling controls cell growth and metabolic homeostasis. Dysregulation of this pathway causes metabolic diseases such as diabetes. Insulin signaling pathways have been extensively studied. Upon insulin binding, the insulin receptor (IR) triggers downstream signaling cascades. The active IR...

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Bibliografiske detaljer
Udgivet i:Exp Mol Med
Main Authors: Hall, Catherine, Yu, Hongtao, Choi, Eunhee
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338473/
https://ncbi.nlm.nih.gov/pubmed/32576931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0456-3
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