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Activating PIK3CA mutation promotes osteogenesis of bone marrow mesenchymal stem cells in macrodactyly

Macrodactyly is a disabling congenital disease characterized by overgrowth of soft tissues and bones, which leads to finger enlargement and joint deformity. The mechanism of bone overgrowth in macrodactyly was rarely understood. In our study bone manifestations of three macrodactyly patients were an...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Cui, Hengqing, Han, Gang, Sun, Bin, Fang, Xia, Dai, Xinyi, Zhou, Shengbo, Mao, Hailei, Wang, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338441/
https://ncbi.nlm.nih.gov/pubmed/32632138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2723-6
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