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Activating PIK3CA mutation promotes osteogenesis of bone marrow mesenchymal stem cells in macrodactyly

Macrodactyly is a disabling congenital disease characterized by overgrowth of soft tissues and bones, which leads to finger enlargement and joint deformity. The mechanism of bone overgrowth in macrodactyly was rarely understood. In our study bone manifestations of three macrodactyly patients were an...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Cui, Hengqing, Han, Gang, Sun, Bin, Fang, Xia, Dai, Xinyi, Zhou, Shengbo, Mao, Hailei, Wang, Bin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338441/
https://ncbi.nlm.nih.gov/pubmed/32632138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2723-6
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