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Secreted frizzled-related protein 2 prevents pressure-overload-induced cardiac hypertrophy by targeting the Wnt/β-catenin pathway

BACKGROUND AND AIM: Secreted frizzled-related protein 2 (sFRP2) has been reported to be involved in cardiovascular diseases. However, its role in cardiac hypertrophy induced by pressure overload is still elusive. We aimed to examine the role of sFRP2 in the development of cardiac hypertrophy in vivo...

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Bibliographic Details
Published in:Mol Cell Biochem
Main Authors: Wei, Wen-Ying, Zhao, Qing, Zhang, Wen-zhong, Wang, Mao-jing, Li, Yan, Wang, Shi-zhong, Zhang, Ning
Format: Artigo
Language:Inglês
Published: Springer US 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338134/
https://ncbi.nlm.nih.gov/pubmed/32632611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-020-03802-x
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