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Secreted frizzled-related protein 2 prevents pressure-overload-induced cardiac hypertrophy by targeting the Wnt/β-catenin pathway

BACKGROUND AND AIM: Secreted frizzled-related protein 2 (sFRP2) has been reported to be involved in cardiovascular diseases. However, its role in cardiac hypertrophy induced by pressure overload is still elusive. We aimed to examine the role of sFRP2 in the development of cardiac hypertrophy in vivo...

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Publicat a:Mol Cell Biochem
Autors principals: Wei, Wen-Ying, Zhao, Qing, Zhang, Wen-zhong, Wang, Mao-jing, Li, Yan, Wang, Shi-zhong, Zhang, Ning
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338134/
https://ncbi.nlm.nih.gov/pubmed/32632611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-020-03802-x
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