Immunopeptidomic Analysis Reveals That Deamidated HLA-bound Peptides Arise Predominantly from Deglycosylated Precursors

The presentation of post-translationally modified (PTM) peptides by cell surface HLA molecules has the potential to increase the diversity of targets for surveilling T cells. Although immunopeptidomics studies routinely identify thousands of HLA-bound peptides from cell lines and tissue samples, in-...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Mei, Shutao, Ayala, Rochelle, Ramarathinam, Sri H., Illing, Patricia T., Faridi, Pouya, Song, Jiangning, Purcell, Anthony W., Croft, Nathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Technological Innovation and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338083/
https://ncbi.nlm.nih.gov/pubmed/32357974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001846
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