Genetically encoded betaxanthin-based small-molecular fluorescent reporter for mammalian cells

We designed and engineered a dye production cassette encoding a heterologous pathway, including human tyrosine hydroxylase and Amanita muscaria 4,5-DOPA dioxygenase, for the biosynthesis of the betaxanthin family of plant and fungal pigments in mammalian cells. The system does not impair cell viabil...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Stücheli, Pascal, Sieber, Simon, Fuchs, David W, Scheller, Leo, Strittmatter, Tobias, Saxena, Pratik, Gademann, Karl, Fussenegger, Martin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337513/
https://ncbi.nlm.nih.gov/pubmed/32421771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa342
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