Llwytho...

Rational design of a small molecule-responsive intramer controlling transgene expression in mammalian cells

Aptamers binding proteins or small molecules have been shown to be versatile and powerful building blocks for the construction of artificial genetic switches. In this study, we present a novel aptamer-based construct regulating the Tet Off system in a tetracycline-independent manner thus achieving c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ausländer, David, Wieland, Markus, Ausländer, Simon, Tigges, Marcel, Fussenegger, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239198/
https://ncbi.nlm.nih.gov/pubmed/21984476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr829
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