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ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer
The autophagy-initiating human ULK complex consists of the kinase ULK1/2, FIP200, ATG13, and ATG101. Hydrogen-deuterium exchange mass spectrometry was used to map their mutual interactions. The N-terminal 640 residues (NTD) of FIP200 interact with the C-terminal IDR of ATG13. Mutations in these regi...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Cell Biol |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Rockefeller University Press
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7337493/ https://ncbi.nlm.nih.gov/pubmed/32516362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201911047 |
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