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TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes

The mechanisms underlying turnover of the nuclear pore complex (NPC) and the component nucleoporins (Nups) are still poorly understood. In this study, we found that the budding yeast Saccharomyces cerevisiae triggers NPC degradation by autophagy upon the inactivation of Tor kinase complex 1. This de...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Tomioka, Yui, Kotani, Tetsuya, Kirisako, Hiromi, Oikawa, Yu, Kimura, Yayoi, Hirano, Hisashi, Ohsumi, Yoshinori, Nakatogawa, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337488/
https://ncbi.nlm.nih.gov/pubmed/32453403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201910063
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