SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

The most severe and fatal infections with SARS-CoV-2 result in the acute respiratory distress syndrome, a clinical phenotype of coronavirus disease 2019 (COVID-19) that is associated with virions targeting the epithelium of the distal lung, particularly the facultative progenitors of this tissue, al...

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Publicat a:bioRxiv
Autors principals: Huang, Jessie, Hume, Adam J., Abo, Kristine M., Werder, Rhiannon B., Villacorta-Martin, Carlos, Alysandratos, Konstantinos-Dionysios, Beermann, Mary Lou, Simone-Roach, Chantelle, Lindstrom-Vautrin, Jonathan, Olejnik, Judith, Suder, Ellen L., Bullitt, Esther, Hinds, Anne, Sharma, Arjun, Bosmann, Markus, Wang, Ruobing, Hawkins, Finn, Burks, Eric J., Saeed, Mohsan, Wilson, Andrew A., Mühlberger, Elke, Kotton, Darrell N.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337394/
https://ncbi.nlm.nih.gov/pubmed/32637964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.30.175695
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