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Glycans on the SARS-CoV-2 Spike Control the Receptor Binding Domain Conformation
The glycan shield of the beta-coronavirus (β-CoV) Spike (S) glycoprotein provides protection from host immune responses, acting as a steric block to potentially neutralizing antibody responses. The conformationally dynamic S-protein is the primary immunogenic target of vaccine design owing to its ro...
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| Publicado no: | bioRxiv |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7337389/ https://ncbi.nlm.nih.gov/pubmed/32637959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.26.173765 |
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