Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant

The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide in a matter of months. Here we show that D614G was more infectious than the ancestral form on human lung cells, colon cells, and cells rendered permissive by ectopic expression of various mammalian ACE2 orthologs...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Yurkovetskiy, Leonid, Wang, Xue, Pascal, Kristen E., Tomkins-Tinch, Christopher, Nyalile, Thomas, Wang, Yetao, Baum, Alina, Diehl, William E., Dauphin, Ann, Carbone, Claudia, Veinotte, Kristen, Egri, Shawn B., Schaffner, Stephen F., Lemieux, Jacob E., Munro, James, Rafique, Ashique, Barve, Abhi, Sabeti, Pardis C., Kyratsous, Christos A., Dudkina, Natalya, Shen, Kuang, Luban, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337374/
https://ncbi.nlm.nih.gov/pubmed/32637944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.04.187757
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados