FPR1 blockade prevents receptor regulation by mitochondrial DAMPs and preserves neutrophil function after trauma

OBJECTIVES: Trauma predisposes to systemic sterile inflammation (SIRS) as well as infection, but the mechanisms linking injury to infection are poorly understood. Mitochondrial debris (MTD) contains formyl peptides (mtFPs). These bind formyl peptide receptor-1 (FPR1), trafficking neutrophils (PMN) t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: Itagaki, Kiyoshi, Kaczmarek, Elzbieta, Kwon, Woon Yong, Chen, Li, Vlková, Barbora, Zhang, Quanzhi, Riça, Ingred, Yaffe, Michael B., Campbell, Yan, Marusich, Michael F., Wang, Ji Ming, Gong, Wang-Hua, Gao, Ji-Liang, Jung, Françoise, Douglas, Garry, Otterbein, Leo E., Hauser, Carl J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337247/
https://ncbi.nlm.nih.gov/pubmed/31939811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000004094
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados