Use of Simulation Strategies to Predict Subtherapeutic Meropenem Exposure Caused by Augmented Renal Clearance in Critically Ill Pediatric Patients With Sepsis

OBJECTIVES: The objectives of this study were to 1) define extent and potential clinical impact of increased or decreased renal elimination of meropenem in children with sepsis, based on analysis of renal function during the first 2 days of PICU stay; and 2) estimate the risk of subtherapeutic merop...

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Detalhes bibliográficos
Publicado no:J Pediatr Pharmacol Ther
Main Authors: Avedissian, Sean N., Skochko, Shannon M., Le, Jennifer, Hingtgen, Sara, Harvey, Helen, Capparelli, Edmund V., Richardson, Andrew, Momper, Jeremiah, Mak, Robert H., Neely, Michael, Bradley, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Pharmacy Advocacy Group 2020
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337137/
https://ncbi.nlm.nih.gov/pubmed/32641911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-25.5.413
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