TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination

Ubiquitination is an essential mechanism in the control of antiviral immunity upon virus infection. Here, we identify a series of ubiquitination-modulating enzymes that are modulated by vesicular stomatitis virus (VSV). Notably, TRIM24 is down-regulated through direct transcriptional suppression ind...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Zhu, Qingchen, Yu, Tao, Gan, Shucheng, Wang, Yan, Pei, Yifei, Zhao, Qifan, Pei, Siyu, Hao, Shumeng, Yuan, Jia, Xu, Jing, Hou, Fajian, Wu, Xuefeng, Peng, Chao, Wu, Ping, Qin, Jun, Xiao, Yichuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336305/
https://ncbi.nlm.nih.gov/pubmed/32324863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192083
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