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Contribution of Lysosome and Sigma Receptors to Neuroprotective Effects of Memantine Against Beta-Amyloid in the SH-SY5Y Cells

Purpose: Memantine is an approved drug for the treatment of Alzheimer’s disease (AD). Autophagy, lysosome dysfunction, and sigma receptors have possible roles in the pathophysiology of AD. Therefore, we aimed to investigate the contribution of sigma receptors and lysosome inhibition to the neuroprot...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Keshavarz, Mojtaba, Farrokhi, Majid Reza, Amirinezhad Fard, Elahe, Mehdipour, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335986/
https://ncbi.nlm.nih.gov/pubmed/32665905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.34172/apb.2020.055
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