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Interfacial Binding Sites for Cholesterol on Kir, Kv, K(2P), and Related Potassium Channels

Inwardly rectifying, voltage-gated, two-pore domain, and related K(+) channels are located in eukaryotic membranes rich in cholesterol. Here, molecular docking is used to detect specific binding sites (“hot spots”) for cholesterol on K(+) channels with characteristics that match those of known chole...

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Pubblicato in:Biophys J
Autore principale: Lee, Anthony G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335934/
https://ncbi.nlm.nih.gov/pubmed/32553129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.05.028
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