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Identification of a Cholesterol-Binding Pocket in Inward Rectifier K(+) (Kir) Channels
Cholesterol is the major sterol component of all mammalian plasma membranes. Recent studies have shown that cholesterol inhibits both bacterial (KirBac1.1 and KirBac3.1) and eukaryotic (Kir2.1) inward rectifier K(+) (Kir) channels. Lipid-sterol interactions are not enantioselective, and the enantiom...
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| 出版年: | Biophys J |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269788/ https://ncbi.nlm.nih.gov/pubmed/25517146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.066 |
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