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Dual-Mode Phospholipid Regulation of Human Inward Rectifying Potassium Channels

The lipid bilayer is a critical determinant of ion channel activity; however, efforts to define the lipid dependence of channel function have generally been limited to cellular expression systems in which the membrane composition cannot be fully controlled. We reconstituted purified human Kir2.1 and...

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Main Authors: Cheng, Wayland W.L., D'Avanzo, Nazzareno, Doyle, Declan A., Nichols, Colin G.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030149/
https://ncbi.nlm.nih.gov/pubmed/21281576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3724
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