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Dual-Mode Phospholipid Regulation of Human Inward Rectifying Potassium Channels

The lipid bilayer is a critical determinant of ion channel activity; however, efforts to define the lipid dependence of channel function have generally been limited to cellular expression systems in which the membrane composition cannot be fully controlled. We reconstituted purified human Kir2.1 and...

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Detalhes bibliográficos
Main Authors: Cheng, Wayland W.L., D'Avanzo, Nazzareno, Doyle, Declan A., Nichols, Colin G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030149/
https://ncbi.nlm.nih.gov/pubmed/21281576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3724
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