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Dual-Mode Phospholipid Regulation of Human Inward Rectifying Potassium Channels

The lipid bilayer is a critical determinant of ion channel activity; however, efforts to define the lipid dependence of channel function have generally been limited to cellular expression systems in which the membrane composition cannot be fully controlled. We reconstituted purified human Kir2.1 and...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Wayland W.L., D'Avanzo, Nazzareno, Doyle, Declan A., Nichols, Colin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030149/
https://ncbi.nlm.nih.gov/pubmed/21281576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3724
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