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Interfacial Binding Sites for Cholesterol on G Protein-Coupled Receptors
A docking procedure is described that allows the transmembrane surface of a G protein-coupled receptor (GPCR) to be swept rapidly for potential binding sites for cholesterol at the bilayer interfaces on the two sides of the membrane. The procedure matches 89% of the cholesterols resolved in publishe...
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| Publicado en: | Biophys J |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Biophysical Society
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6506644/ https://ncbi.nlm.nih.gov/pubmed/31010663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.03.025 |
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