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Interfacial Binding Sites for Cholesterol on G Protein-Coupled Receptors

A docking procedure is described that allows the transmembrane surface of a G protein-coupled receptor (GPCR) to be swept rapidly for potential binding sites for cholesterol at the bilayer interfaces on the two sides of the membrane. The procedure matches 89% of the cholesterols resolved in publishe...

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Detalles Bibliográficos
Publicado en:Biophys J
Autor Principal: Lee, Anthony G.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506644/
https://ncbi.nlm.nih.gov/pubmed/31010663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.03.025
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