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A terminal α3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii

Skp1, a subunit of E3 Skp1/Cullin-1/F-box protein ubiquitin ligases, is modified by a prolyl hydroxylase that mediates O(2) regulation of the social amoeba Dictyostelium and the parasite Toxoplasma gondii. The full effect of hydroxylation requires modification of the hydroxyproline by a pentasacchar...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Mandalasi, Msano, Kim, Hyun W., Thieker, David, Sheikh, M. Osman, Gas-Pascual, Elisabet, Rahman, Kazi, Zhao, Peng, Daniel, Nitin G., van der Wel, Hanke, Ichikawa, H. Travis, Glushka, John N., Wells, Lance, Woods, Robert J., Wood, Zachary A., West, Christopher M.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335778/
https://ncbi.nlm.nih.gov/pubmed/32414843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013792
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