Characterization of a cytoplasmic glucosyltransferase that extends the core trisaccharide of the Toxoplasma Skp1 E3 ubiquitin ligase subunit

Skp1 is a subunit of the SCF (Skp1/Cullin 1/F-box protein) class of E3 ubiquitin ligases that are important for eukaryotic protein degradation. Unlike its animal counterparts, Skp1 from Toxoplasma gondii is hydroxylated by an O(2)-dependent prolyl-4-hydroxylase (PhyA), and the resulting hydroxyproli...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rahman, Kazi, Mandalasi, Msano, Zhao, Peng, Sheikh, M. Osman, Taujale, Rahil, Kim, Hyun W., van der Wel, Hanke, Matta, Khushi, Kannan, Natarajan, Glushka, John N., Wells, Lance, West, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682971/
https://ncbi.nlm.nih.gov/pubmed/28928220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809301
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