O(2) sensing–associated glycosylation exposes the F-box–combining site of the Dictyostelium Skp1 subunit in E3 ubiquitin ligases

Skp1 is a conserved protein linking cullin-1 to F-box proteins in SCF (Skp1/Cullin-1/F-box protein) E3 ubiquitin ligases, which modify protein substrates with polyubiquitin chains that typically target them for 26S proteasome-mediated degradation. In Dictyostelium (a social amoeba), Toxoplasma gondi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sheikh, M. Osman, Thieker, David, Chalmers, Gordon, Schafer, Christopher M., Ishihara, Mayumi, Azadi, Parastoo, Woods, Robert J., Glushka, John N., Bendiak, Brad, Prestegard, James H., West, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704474/
https://ncbi.nlm.nih.gov/pubmed/28928219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809160
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