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Novel Regulation of Skp1 by the Dictyostelium AgtA α-Galactosyltransferase Involves the Skp1-binding Activity of Its WD40 Repeat Domain

The role of Skp1 as an adaptor protein that links Cullin-1 to F-box proteins in E3 Skp1/Cullin-1/F-box protein (SCF) ubiquitin ligases is well characterized. In the social amoeba Dictyostelium and probably many other unicellular eukaryotes, Skp1 is modified by a pentasaccharide attached to a hydroxy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schafer, Christopher M., Sheikh, M. Osman, Zhang, Dongmei, West, Christopher M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979368/
https://ncbi.nlm.nih.gov/pubmed/24550398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.528679
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