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miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells

Many cancers maintain an inflammatory microenvironment to promote their growth. Lung cancer is of particular importance, as it is the deadliest cancer worldwide. One inflammatory pathway commonly dysregulated in cancer is the metabolism of arachidonic acid (AA) by Cyclooxygenase-2 (COX-2) and micros...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Monteleone, Nicholas J., Lutz, Carol S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335672/
https://ncbi.nlm.nih.gov/pubmed/32655834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27614
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