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miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells

Many cancers maintain an inflammatory microenvironment to promote their growth. Lung cancer is of particular importance, as it is the deadliest cancer worldwide. One inflammatory pathway commonly dysregulated in cancer is the metabolism of arachidonic acid (AA) by Cyclooxygenase-2 (COX-2) and micros...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Monteleone, Nicholas J., Lutz, Carol S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335672/
https://ncbi.nlm.nih.gov/pubmed/32655834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27614
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