EBV renders B cells susceptible to HIV-1 in humanized mice

HIV and EBV are human pathogens that cause a considerable burden to worldwide health. In combination, these viruses are linked to AIDS-associated lymphomas. We found that EBV, which transforms B cells, renders them susceptible to HIV-1 infection in a CXCR4 and CD4-dependent manner in vitro and that...

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Pubblicato in:Life Sci Alliance
Autori principali: McHugh, Donal, Myburgh, Renier, Caduff, Nicole, Spohn, Michael, Kok, Yik Lim, Keller, Christian W, Murer, Anita, Chatterjee, Bithi, Rühl, Julia, Engelmann, Christine, Chijioke, Obinna, Quast, Isaak, Shilaih, Mohaned, Strouvelle, Victoria P, Neumann, Kathrin, Menter, Thomas, Dirnhofer, Stephan, Lam, Janice KP, Hui, Kwai F, Bredl, Simon, Schlaepfer, Erika, Sorce, Silvia, Zbinden, Andrea, Capaul, Riccarda, Lünemann, Jan D, Aguzzi, Adriano, Chiang, Alan KS, Kempf, Werner, Trkola, Alexandra, Metzner, Karin J, Manz, Markus G, Grundhoff, Adam, Speck, Roberto F, Münz, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Life Science Alliance LLC 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335381/
https://ncbi.nlm.nih.gov/pubmed/32576602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000640
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