EBV renders B cells susceptible to HIV-1 in humanized mice

HIV and EBV are human pathogens that cause a considerable burden to worldwide health. In combination, these viruses are linked to AIDS-associated lymphomas. We found that EBV, which transforms B cells, renders them susceptible to HIV-1 infection in a CXCR4 and CD4-dependent manner in vitro and that...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: McHugh, Donal, Myburgh, Renier, Caduff, Nicole, Spohn, Michael, Kok, Yik Lim, Keller, Christian W, Murer, Anita, Chatterjee, Bithi, Rühl, Julia, Engelmann, Christine, Chijioke, Obinna, Quast, Isaak, Shilaih, Mohaned, Strouvelle, Victoria P, Neumann, Kathrin, Menter, Thomas, Dirnhofer, Stephan, Lam, Janice KP, Hui, Kwai F, Bredl, Simon, Schlaepfer, Erika, Sorce, Silvia, Zbinden, Andrea, Capaul, Riccarda, Lünemann, Jan D, Aguzzi, Adriano, Chiang, Alan KS, Kempf, Werner, Trkola, Alexandra, Metzner, Karin J, Manz, Markus G, Grundhoff, Adam, Speck, Roberto F, Münz, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335381/
https://ncbi.nlm.nih.gov/pubmed/32576602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000640
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