A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome

Recent studies of bacterial DNA replication have led to a picture of the replisome as an entity that freely exchanges DNA polymerases and displays intermittent coupling between the helicase and polymerase(s). Challenging the textbook model of the polymerase holoenzyme acting as a stable complex coor...

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Publicado en:Mol Cell
Main Authors: Monachino, Enrico, Jergic, Slobodan, Lewis, Jacob S., Xu, Zhi-Qiang, Lo, Allen T.Y., O’Shea, Valerie L., Berger, James M., Dixon, Nicholas E., van Oijen, Antoine M.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335327/
https://ncbi.nlm.nih.gov/pubmed/32464091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.04.037
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