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Unique and Shared Roles for Histone H3K36 Methylation States in Transcription Regulation Functions

Set2 co-transcriptionally methylates lysine 36 of histone H3 (H3K36), producing mono-, di-, and trimethylation (H3K36me1/2/3). These modifications recruit or repel chromatin effector proteins important for transcriptional fidelity, mRNA splicing, and DNA repair. However, it was not known whether the...

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Библиографические подробности
Опубликовано в: :Cell Rep
Главные авторы: DiFiore, Julia V., Ptacek, Travis S., Wang, Yi, Li, Bing, Simon, Jeremy M., Strahl, Brian D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334899/
https://ncbi.nlm.nih.gov/pubmed/32521276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107751
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