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Phosphocholine accumulation and PHOSPHO1 depletion promote adipose tissue thermogenesis
Phosphocholine phosphatase-1 (PHOSPHO1) is a phosphocholine phosphatase that catalyzes the hydrolysis of phosphocholine (PC) to choline. Here we demonstrate that the PHOSPHO1 transcript is highly enriched in mature brown adipose tissue (BAT) and is further induced by cold and isoproterenol treatment...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7334538/ https://ncbi.nlm.nih.gov/pubmed/32554489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916550117 |
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