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The AAA+ ATPase Msp1 is a processive protein translocase with robust unfoldase activity
Msp1 is a conserved eukaryotic AAA+ ATPase localized to the outer mitochondrial membrane, where it is thought to extract mislocalized tail-anchored proteins. Despite recent in vivo and in vitro studies supporting this function, a mechanistic understanding of how Msp1 extracts its substrates is still...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7334508/ https://ncbi.nlm.nih.gov/pubmed/32541053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920109117 |
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