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The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading
Pex1 and Pex6 form a heterohexameric motor essential for peroxisome biogenesis and function, and mutations in these AAA-ATPases cause most peroxisome-biogenesis disorders in humans. The tail-anchored protein Pex15 recruits Pex1/Pex6 to the peroxisomal membrane, where it performs an unknown function...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5762779/ https://ncbi.nlm.nih.gov/pubmed/29321502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02474-4 |
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