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The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits
Pex1 and Pex6 are Type-2 AAA+ ATPases required for the de-novo biogenesis of peroxisomes. Mutations in Pex1 and Pex6 account for the majority of the most severe forms of peroxisome biogenesis disorders in humans. Here we show that the ATP-dependent complex of Pex1 and Pex6 from S. cerevisiae is a he...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355278/ https://ncbi.nlm.nih.gov/pubmed/25659908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.01.019 |
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