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Structure of the RECK CC domain, an evolutionary anomaly

Five small protein domains, the CC-domains, at the N terminus of the RECK protein, play essential roles in signaling by WNT7A and WNT7B in the context of central nervous system angiogenesis and blood–brain barrier formation and maintenance. We have determined the structure of CC domain 4 (CC4) at 1....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chang, Tao-Hsin, Hsieh, Fu-Lien, Smallwood, Philip M., Gabelli, Sandra B., Nathans, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334487/
https://ncbi.nlm.nih.gov/pubmed/32541044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006332117
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